Oral moniliasis occurs frequently in newborn infants and probably is exceeded only by impetigo neonatorum in its incidence in nurseries for newborn infants. This study was undertaken to investigate further some of the factors which may be related to the incidence, the source and the spread of oral moniliasis in newborn infants.
Oral swabs were obtained from apparently normal newborn infants in order to investigate the frequency with which they contained Monilia and to study oral moniliasis preclinically, if perchance thrush developed later in any of the infants. Vaginal swabs were obtained from the mothers of some of these infants during labor and/or at delivery in order to determine the relationship between maternal vaginal and infantile oral moniliasis. Whenever thrush of the mouth became clinically manifest in infants not in the group being studied, laboratory confirmation of the diagnosis was attempted by culturing oral swabs for Monilia (Candida) albicans.