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REGULATION OF LEVEL OF VITAMIN A IN BLOOD OF NEWBORN INFANTS

J. M. LEWIS, M.D.; O. BODANSKY; L. M. SHAPIRO, M.D.
Am J Dis Child. 1943;66(5):503-510. doi:10.1001/archpedi.1943.02010230035003.
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PART 1  In previous communications 1 we reported that the concentration of vitamin A in the blood gave some indication of the degree of vitamin A storage in the body. Thus, low blood levels were usually associated with little or no storage in the liver of the rat, whereas high blood levels were accompanied by large stores; intermediate blood levels were of less significance, inasmuch as they were found to be associated with both large and small amounts of vitamin A in the liver.The results of studies which we carried out on infants coincided, in general, with those obtained in studies on rats and indicated the practical importance of the blood level of vitamin A in the estimation of the vitamin A status of a subject. In febrile conditions, however, there is a rapid lowering of the vitamin A concentration in the blood, which is not necessarily accompanied by

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