We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Case Reports |


Am J Dis Child. 1943;66(4):404-412. doi:10.1001/archpedi.1943.02010220057006.
Text Size: A A A
Published online

In 1929 von Gierke1 reported his first case and described the glycogen disease bearing his name. Snapper and van Creveld2 had reported an extensive clinical study of a case the year before, and abnormal accumulations of glycogen had been recognized post mortem in livers previously. "Glycogen disease," as the term was used by van Creveld3 in his excellent review of the syndrome in 1939 and by others, has come to include, as pointed out by Mason and Andersen4 recently, a variety of clinical and pathologic pictures. In general there is a disorder of carbohydrate metabolism beginning at a very early age and characterized by storage of glycogen in abnormally large quantities in various organs, especially the liver, the kidneys and the heart. The causes may not necessarily be similar. Mason and Andersen4 made a tentative classification of the forms of the disease as described in


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.