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Case Reports |


Am J Dis Child. 1942;64(3):492-496. doi:10.1001/archpedi.1942.02010090094012.
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Since the original descriptions by Tay in 1881 and Sachs in 1887 of amaurotic familial idiocy in infants, a great deal of knowledge has been added to the subject, and it is now recognized that this condition exists not only in the form of (a) infantile amaurotic familial idiocy as originally described but in three additional forms, namely (b) the late infantile type, (c) the juvenile type and (d) the adult type.1 As the cases reported in this paper are instances of the classic form of amaurotic familial idiocy, to which the name Tay-Sachs disease has been given, a brief description of the disease will be limited to this form only and the others will be omitted as being beyond the scope of this presentation. Tay-Sachs disease is uncommon, though not rare; and while cases have been reported for the past fifty years, a search of the literature available


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