The purpose of this paper is to discuss briefly a few of the less well known causes of the fact that the requirement for carbohydrates in the diet of infants and children is higher than that in the diet of older persons.
The normal diet of the breast-fed infant 3 months of age contains, in percentage of the total calories per kilogram of body weight per day, about four times more carbohydrate than the normal diet of a 6 year old child and ten times more than the diet of an adult (table 1). It is clear that here is a problem that is as important and interesting to the biologist as to the pediatrician. It is a daily experience of the latter to observe that the addition of 20 to 25 Gm. of sugar to the diet of an infant produces within twenty-four hours a gain in weight of