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PROGRESS IN PEDIATRICS |

A CLINICAL STUDY OF TETANUS

RALPH SPAETH, M.D.
Am J Dis Child. 1940;60(1):130-169. doi:10.1001/archpedi.1940.02000010139010.
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During the early part of the summer of 1932, 3 fatal cases of tetanus in children were observed within a relatively short time. The routine treatment of the patients and of those hospitalized previously had consisted of general ward care, antitoxin administered by the intrathecal route in combination with other routes, emphasis on radical surgical care of the local lesions and variable degrees of attention to sedative therapy. On the suggestion of the staff of the Children's Hospital, I decided to reinvestigate the subject of tetanus in the hope that the treatment might be improved. This presentation gives the results of my study and of the application of certain newer therapeutic measures in the management of 33 patients with tetanus. Table 1 summarizes the significant data of this series. Included as a basis for comparison is a discussion of the observations made on an equal number of patients treated according

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