0
Case Reports |

LOCALIZED ABSENCE OF THE GANGLION CELLS OF THE MYENTERIC PLEXUS IN CONGENITAL MEGACOLON

MARY ELIZABETH TIFFIN, M.D.; LOREN ROSCOE CHANDLER, M.D.; HAROLD K. FABER, M.D.
Am J Dis Child. 1940;59(5):1071-1082. doi:10.1001/archpedi.1940.01990160145010.
Text Size: A A A
Published online

The title of Hirschsprung's paper,1 published in 1887, on the disease which bears his name reads, in translation, "Sluggishness of Stool in the Newborn Resulting from Dilatation and Hypertrophy of the Colon." It indicates what is now a well established fact, that there is a group of cases of so-called congenital megacolon in which, despite obvious manifestations of incomplete, localized intestinal obstruction occurring at various levels of the large bowel, no gross stricture or stenosis can be demonstrated. The absence of an organic, macroscopic cause for the obstruction is all the more striking in that almost identical manifestations are found in other cases in which a mechanical cause is evident, such as stricture, diaphragm formation of the rectal valves and inflammatory lesions causing chronic spasm.

No satisfactory explanation based on anatomic evidence has as yet been generally accepted, and recent discussions have dealt largely with a functional cause, particularly

Topics

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();