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METABOLIC STUDY OF FIVE CHILDREN WITH NEPHROTIC SYNDROME:  II. FAT AND PROTEIN METABOLISM AND CREATININE AND CREATINE OUTPUT

CHI CHE WANG, PH.D.; CORINNE HOGDEN, M.S.; IDA GENTHER, PH.D.
Am J Dis Child. 1939;58(1):29-36. doi:10.1001/archpedi.1939.01990070041003.
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In a previous paper1 the clinical observations, the results of examination of the blood, the values for basal metabolism and the data on energy exchange of 5 children with the nephrotic syndrome were reported. Studies of the fat and protein metabolism and of the excretion of creatinine and creatine of these children during the same experimental periods are reported in this communication.

EXPERIMENTAL METHOD  The technic of feeding the subjects and of collecting and preparing specimens for chemical analyses and the methods employed for the determination of values for fat, nitrogen, creatinine and creatine have been described in previous papers.2 Each experimental period consisted of at least two consecutive intervals of three days each preceded by a preliminary period of not less than five days. The medication and the daily record of body weight, protein intake and urine and albumin output during this study were indicated in charts

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