Although a large number of cases of Gaucher's disease have been reported and many excellent discussions have appeared1 concerning the primary diseases of lipid metabolism, which include Gaucher's disease, Hand-Schüller-Christian disease and Niemann-Pick disease, studies of two Negro siblings are presented here. These patients had the changes of Gaucher's disease in the spleen, liver, lymph nodes, blood, bone marrow and conjunctiva.
REPORT OF CASES
Case 1.—Marshall L., a boy aged 7 years, was first admitted to Duke Hospital on July 7, 1936, with the complaint of having had a large stomach for the past three or four years. His sister Mary, aged 9 years, was admitted at the same time with a similar complaint. The father, aged 29 years, and the mother, aged 30 years, were living and well. There had been one other pregnancy, ending in a miscarriage at three months. The family history was otherwise noncontributory.The