A white female infant with numerous raised gray nodules from 1 to 2 mm. in diameter studding the alveolar process of each jaw was observed in the service for the new-born of one of us (H. S.). The mother of the child, 24 years of age, had been in good health during pregnancy, and the delivery was normal. There had been one previous pregnancy, with an abortion at two months. The oral condition of the infant was noted immediately after birth. The lesions (fig. 1) persisted throughout the neonatal period, which with the exception of a mild irritation of the skin was uneventful.
On the fourteenth day a small piece of tissue including one of the nodules was removed from the mucous membrane over the alveolar process in the region of the right upper temporary cuspid crypt. The tissue was fixed in a 10 per cent dilution of solution of