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EXCRETION OF DRUGS IN MILK

NATHANIEL T. KWIT, M.D.; ROBERT A. HATCHER, M.D.
Am J Dis Child. 1935;49(4):900-904. doi:10.1001/archpedi.1935.01970040068008.
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This is the third paper from the laboratory of Cornell University Medical College dealing with the elimination of drugs in human milk.1 Reed2 presented an excellent review of the literature up to 1908; Joachimovits3 gave a bibliography of about twenty-five references. Terwilliger and Hatcherlb have discussed the literature briefly, and we shall discuss only a few papers dealing with the subject.

Recently Joachimovits employed the Hanauer analytical lamp for the detection of traces of numerous substances in milk, but his investigation was limited to substances which are fluorescent, and it is interesting chiefly because his method permits of the detection of traces of many substances in the mother's milk. He made no quantitative determination of any of these substances.

Van der Bogert4 reported the case of an infant in whom a papulopustular eruption developed which was attributed to bromide in the milk of the mother,

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