In this monograph of moderate length Bouman has formulated an extremely able and balanced presentation of his subject as it stands today. In a sense diffuse sclerosis is a disease of rather recent recognition, dating from the precise histopathologic description given by Schilder in 1912. But with attention so sharply focused, many reports have appeared since then, and all the more important of these, together with the older observations, are surveyed in this work. It is gratifying to note that the author employs the older and less committal term "diffuse sclerosis" rather than the term "encephalitis periaxialis diffusa" conferred on the disease by Schilder.
It is Bouman's prime purpose to discover by his analysis some sort of order in what has been the greatest diagnostic confusion concerning this disease. To this end he has drawn on the data of some hundred cases, including the original and notable contribution of six