Acute necrosis of the liver is a rare condition in children, as evidenced by the fact that Rolleston1 found only 43 cases reported up to 1929: for that reason this case is reported in full.
REPORT OF CASE
History.—Z. C., aged 3½ years, a white girl, had a father, mother and two sisters who were living and well. Both parents denied having venereal infection. The mother had had one miscarriage, the cause of which was unknown. There was no history of chronic or recent acute illness in the immediate family. The parents were in very poor circumstances, and had always lived on a farm. The patient, as far as the mother knew, had never been sick except for an occasional cold and infrequent attacks of vomiting. She had never received medicine except an occasional dose of "salts" and "black draught." For several months before the onset she had