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Case Reports |


Am J Dis Child. 1934;48(2):346-354. doi:10.1001/archpedi.1934.01960150105009.
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While the "punched-out" areas found on roentgenograms of the skull produced by lipoid infiltrations of the reticulo-endothelial system have been reported many times, roentgen evidence of the course of an analogous lesion of the spine with clinical findings of xanthomatosis has not been reported in the literature. The present report is of two-fold interest in that such a lesion was found and that the patient apparently recovered completely without special treatment. It is of further interest from a diagnostic standpoint. Schüller1 (1915) and Christian2 (1920) described associated exophthalmos and diabetes, now believed to be complications as the result of nonsupporting soft lipoid deposits in the skull. Until Rowland's3 illuminating descriptions many cases of xanthomatosis were thought to be malignant tumors4 or tuberculosis. Hand5 in 1893 was the first to describe a case fitting the Schüller-Christian syndrome, but the pathologic changes were mistakenly reported as due


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