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Case Reports |

APLASTIC ANEMIA

HARRY M. GREENWALD, M.D.
Am J Dis Child. 1934;47(2):360-373. doi:10.1001/archpedi.1934.01960090101010.
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Aplastic anemia was first described by Ehrlich1 in 1888. Since then a change in the nomenclature has been suggested by Frank,2 who terms the disease hemorrhagic aleukia and panmyelophthisis. Pappenheim3 also considers the term aregenerative anemia more descriptive of this condition. A study of this case is presented because of the unusually small number of cases reported in the literature and because of the many uncertainties which still surround this condition. It is hoped that light may be shed on this disease by a study of the clinical and hematologic pictures and of the pathologic changes presented in the case reported. The cases of idiopathic aplastic anemia reported in the literature up to the present may be divided into three groups, depending on the presence or absence of pathologic studies and on the final outcome of the case. The first group comprises those cases in which there

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