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Case Reports |

AGRANULOCYTOSIS IN CHILDHOOD

THURMAN B. GIVAN, M.D.; BENJAMIN SHAPIRO, M.D.
Am J Dis Child. 1933;46(3):550-560. doi:10.1001/archpedi.1933.01960030079007.
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Agranulocytic angina as such was first described by Werner Schultz in 1922.1 His primary concepts and his later acceptances2 of variabilities, owing to the multiplicity of true cases reported, are too widely acknowledged to permit of repetition here. Neither Schultz nor his early followers seemed to admit the possibility of this syndrome occurring in childhood, though previous to his report some instances had been recorded. Schwartz3 reported a case in a child in 1904, and Leale4 presented a case in an infant with recurrent attacks of furunculosis associated with leukopenia. This case will be discussed in greater detail later.

Following the admission to the Long Island College Hospital of the patient whose case is reported in this paper, a review of the literature of agranulocytosis in childhood was made with the idea of charting and analyzing the cases to determine whether any could be classified as

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