In this section is presented an abstract of the charts of sixteen syphilitic infants who came to autopsy. The youngest was 1 month and the oldest 13 months of age. Thirteen were not over 3 months.
In each of the sixteen cases, evidence of pathologic changes in the bones was noted in the x-ray film. In all but two instances, the bone removed at autopsy for microscopic examination was selected because it presented the most marked evidence of the disease on the x-ray films. An endeavor was made, however, to use the bones of the lower extremities for section, as they presented a larger field for microscopy and offered more normal bone in association with the abnormal for comparative study.
The specimens offered for study range from the cases showing the earliest changes in the bone at the epiphysial-diaphysial junction to the most advanced type of osteochondritis showing extreme lawlessness