During recent years the literature has afforded a number of examples of typical pellagroid syndrome associated with or following some specific gastro-intestinal disease.
Rolph,1 in 1916, recorded the case of a woman, aged 41, who was seen in March, 1915. At that time she gave a history of excessive expectoration and increasing weakness and dysphagia of three months' duration. When seen again three months later, she had developed pellagroid dermatitis of the face, hands and forearms and was extremely emaciated. Death occurred the following month, and the autopsy showed carcinoma that involved the lesser curvature and cardiac orifice of the stomach.
In 1919, Bryan2 described the case of a man, aged 49, who for twenty years had had a condition suggestive of peptic ulcer. For two years he had lost weight, and for twelve months he had vomited increasingly, during which time a typical pellagroid dermatitis and stomatitis