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December 1928, Vol 36, No. 6 >
Other Articles | December 1928

ACTIVATED ERGOSTEROL IN THE TREATMENT OF RICKETS

SAMUEL KARELITZ, M.D.
Am J Dis Child. 1928;36(6):1108-1120. doi:10.1001/archpedi.1928.01920300017002.
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In an attempt to repeat the experiments of Hume and Smith,1 Chick and Tazelaar2 showed that it was not the irradiated air which cured the rachitic rats, but that the cure was effected through the ingested irradiated, excreta-soiled sawdust of the cages. Nelson and Steenbock3 showed that nonirradiated rachitic rats kept in the same cages with irradiated rachitic rats were cured, not by the secondary rays emitted from the latter, but by the excreta which they ate. Steenbock and Black4 induced antirachitic properties into rat rations by exposing the foods to ultraviolet rays. Hess5 and Steenbock and Nelson6 almost simultaneously reported the curing of rickets in rats by feeding irradiated food substances. Hess was successful in using irradiated rat skins as treatment for rickets. With irradiated liquid milk, Kramer7 successfully treated infants who had rickets. Rosenheim8 and György, Yenke and Popoviciu9

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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