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Am J Dis Child. 1927;33(3):394-403. doi:10.1001/archpedi.1927.04130150033002.
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Periosteal elevation in childhood is not infrequently encountered, and is usually associated with scurvy or congenital syphilis. In the last year I had the opportunity to observe two children with neuroblastoma and leukemia, respectively, both of whom had roentgen-ray evidence of periosteal elevation of the long bones.

REPORT OF CASES  Case 1.—History.—M. G.,boy, aged 3 years, was admitted to the hospital June 11, 1925, with the complaint of weakness, swelling of the fingers, and anemia of several months' duration. His family history was negative. The Wassermann test of the blood of both parents and of a brother was negative. The patient's past history was irrelevant. He weighed 7 pounds (3.2 Kg.) at birth, which was normal. He was breast fed for three months, then successfully weaned. He developed normally and enjoyed good health except for pneumonia at the age of 18 months and diphtheria at 2 years (for


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