The following observation concerning enlargement of the spleen during the eruptive stage of measles was made during the winter of 1922, and was reported at a meeting of the St. Louis Pediatric Society, Oct. 26, 1923. Two hundred sixty-four cases of measles made up the series on which conclusions were based. It was, however, deemed wise to repeat the study in some later epidemic of this disease before publishing the data then acquired, and to this end an additional 133 cases were observed during the winters of 1923 and 1924, the information obtained on this point being added to the original paper in Chart 2.
It is, of course, a common thing in clinical work to encounter a spleen that can be felt below the costal margin, but the almost abrupt appearance of the spleen during the eruptive stage of measles, and the suddenness of its disappearance as the rash