The following patients, Cases 1 and 2, came under observation in the the pediatric and orthopedic departments of the Allegheny General Hospital.
REPORT OF CASES
—F. C., a boy, aged 6 years, of Italian parentage was born in western Pennsylvania. He was one of thirteen children. There were seven brothers and four sisters living who were in good health. Two brothers died in infancy from unknown causes. There was no family history of tuberculosis, syphilis or alcoholism. The previous history of the patient was good. He had had no infectious diseases. At birth there was a marked swelling of the right leg. He had had attacks of high fever, coming on suddenly and lasting about eight or ten days, accompanied by convulsions, vomiting and severe pains in the right lower extremity. These attacks came periodically at intervals of about six or seven months, the last one occurring about