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CONTRIBUTION TO THE STUDY OF MYOCARDITIS IN CHILDHOOD WITH PARTICULAR REFERENCE TO ISOLATED ACUTE MYOCARDITIS AND TO THE POSSIBLE RELATION OF MYOCARDITIS TO STATUS THYMICOLYMPHATICUS

Am J Dis Child. 1924;28(5):647. doi:10.1001/archpedi.1924.04120230123011.
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ABSTRACT

The author, in this monograph, discusses the subject of myocarditis in childhood, with particular reference to two phases: the occurrence of isolated acute myocarditis, and the possible relation of the status thymicolymphaticus as a predisposing factor or actual factor in the development of this condition.

His conclusions are based on careful observation of material from the pathologic anatomic Institute of Basel, and comprises 793 necropsies, of which 530 were on children ranging in age from birth up to 15 years, and 263 on prematurely born infants. In practically all of the material microscopic examination of the heart muscle was made.

Status thymicolymphaticus was definitely established in only thirty-two cases. The criteria on which the diagnosis of this condition was based consisted in definite and unmistakable enlargement, or hypertrophy, of the thymus gland associated with general enlargement of all lymphatic glands and structures, including hypoplastic changes in the suprarenals. Interstitial infiltration

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