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Am J Dis Child. 1923;26(2):117-131. doi:10.1001/archpedi.1923.04120140016003.
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For many years, clinicians have been familiar with certain of the features which characterize the roentgenograms of rachitic human bones; but a careful analysis of them has not been made, nor has the interpretation of the picture in the light of histologic alterations received any great attention. This investigation, which was begun at, the suggestion of Dr. E. A. Park and carried on largely through his continued interest, was undertaken with a view to ascertaining the anatomic basis for the roentgen-ray changes in the skeleton in rickets.

METHOD  The bones selected for study were cleaned of surrounding tissues and cut into slices from one-eighth to one-quarter inch thick through the epiphyseodiaphyseal junction. Roentgenograms were obtained, and the slices were then used for the preparation of histologic sections. Some of the tissues were partially decalcified in Müller's fluid; but in many instances, it was found possible to cut sections without preliminary


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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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