0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Other Articles |

SPASMOPHILIA AND THE ALKALI RESERVE OF THE BLOOD

JOSEPH K. CALVIN, S.B., M.D.; MAXWELL P. BOROVSKY, S.B., M.D.
Am J Dis Child. 1922;23(6):493-495. doi:10.1001/archpedi.1922.01910420024004.
Text Size: A A A
Published online

Wilson and his co-workers1 pointed out that in parathyroidectomized dogs, just previous to the attacks of tetany, an increased alkalinity of the blood develops, a condition termed by them "alkalosis," which is neutralized by the acid products generated by the tetanic contractions of the musculature. Recently Grant and Goldman2 have shown that forced respiration may cause symptoms of tetany to appear in the human. In these cases the underlying factor appears to be an "alkalosis." The forced breathing causes an excess of carbon dioxid to be exhaled from the lungs, thereby reducing the amount in the blood. This results in an increased alkalinity of the blood. However, they observed that the tetanic movements apparently produce acid products which tend to compensate for the increased alkalinity until a readjustment takes place.

Clinically it has at times been noted3 that after the therapeutic administration of sodium bicarbonate for acidosis,

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();