Although an extensive literature has accumulated on the diagnostic significance of protein sensitization tests in certain disease conditions, no attempt has hitherto been made to examine a large number of normal children for possible potential anaphylactic cases; nor have we been able to find any comparison between the incidence of protein sensitization in a large number of normal and abnormal subjects. The present widespread general interest in protein sensitization, first clinically and conclusively demonstrated by Schloss1 and later by the voluminous and epochal researches of Walker,2 suggested the necessity of this work.
It is the aim of this paper to show:
The incidence of protein sensitization in the normal child.
The relative frequency of sensitization to the specific protein in relationship to age and diet.
The relative frequency of sensitization to horse serum in those who have and those who have not been injected with