—William B., 9½ years of age, born in Jersey City, N. J., of Italian parentage, has been under observation at the Cornell Children's Clinic for the past two years.
—His paternal history, as far as known, is free from hemophilia. On his mother's side the disease can be traced back two generations. His maternal grandmother died of tuberculosis. Whether she had any symptoms of hemophilia is doubtful. She had twelve children, several of whom died of tuberculosis. A history was obtained of only six of these children, two sons and four daughters. One of the boys died of tuberculosis. He was not considered a bleeder. The other died of hemorrhage when 18 years of age. He was a bleeder. One of the girls gave a history of purpuric spots, spontaneous ecchymosis and bruises following trauma from childhood. Of her offspring, two children, a boy and a girl,