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FOCAL LESIONS PRODUCED IN THE RABBIT BY COLON BACILLI ISOLATED FROM PYELO. CYSTITIS CASESN

HENRY F. HELMHOLZ, M.D.; CAROL BEELER
Am J Dis Child. 1917;14(1):5-24. doi:10.1001/archpedi.1917.01910070012002.
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The mode of infection in pyelocystitis of the infant and child is still far from settled. Much evidence has been brought forward for each of the three routes of infection, the hematogenous, the lymphogenous, and the ascending. In each case the evidence adduced is generalized, and the route of infection made probable by the investigator's observation is claimed as the only possible one. De facto, these observations do not at all preclude the other routes of infection. When we examine the facts as they are at the present time we realize that we do not know what portion of the urinary tract is infected in the condition that is usually termed pyelocystitis. We do know that those cases that come to necropsy usually show some involvement of the kidney pelvis, but that does not prove that a great many of the cases that we see with pus in the catheterized

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