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Review Article |

Retinal Hemorrhages in Children:  The Role of Intracranial Pressure

Tiffany Shiau, MHS; Alex V. Levin, MD, MHSc
Arch Pediatr Adolesc Med. 2012;166(7):623-628. doi:10.1001/archpediatrics.2012.46.
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Published online

Objective  To evaluate the role of intracranial pressure (ICP) in the production of retinal hemorrhage in young children.

Design  Review of published clinical, postmortem, and experimental research findings worldwide pertinent to our review objective. We used PubMed, MEDLINE, and Ovid Evidence-Based Medicine Reviews as well as references found in other published articles to conduct searches.

Main Exposures  Increased ICP from various etiologies.

Main Outcome Measure  Hemorrhagic retinopathy, in particular with extension to the periphery, multiple layers, and too-numerous-to-count hemorrhages. The review also considers additional intraocular findings such as retinoschisis and perimacular folds.

Results  In general, elevated ICP does not cause extensive hemorrhagic retinopathy. Papilledema may be associated with a small number of hemorrhages on or around the optic disc. There are isolated case reports that severe hyperacute ICP elevation, unlike the subacute pressure increase in abusive head injury, in children may rarely result in extensive retinal hemorrhage. These diagnoses are readily distinguished from child abuse.

Conclusions  In the absence of the few readily recognizable alternate scenarios, extensive retinal hemorrhage in very young children is not secondary to isolated elevated ICP.

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Figures

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Grahic Jump Location

Figure 1. Traumatic macular retinoschisis of an infant with abusive head trauma. Photograph shows the posterior pole including the optic nerve (asterisk) and hypopigmented circumlinear retinal fold (arrows). The hump in the vessel created by the fold can be seen where the vessels cross. The arc highlights the 3-dimensional appreciation of the elevated internal limiting membrane of the retina creating a domed cavity involving the macula. There is no blood within the cavity in this child.

Place holder to copy figure label and caption
Grahic Jump Location

Figure 2. Posterior pole of the left eye and extending into the midperiphery of the retina (at edges of image) of an infant with abusive head trauma. Image shows optic nerve (asterisk), a preretinal hemorrhage (note how it lies over a retinal vessel) (short arrows), and flame hemorrhage with characteristic linear appearance (long arrows).

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

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