Accepted for Publication: December 7, 2011.
Published Online: February 6, 2012. doi:10.1001/archpediatrics.2011.1785
Author Contributions: Study concept and design: Nachman, Williams, Hodge, Heston, and Gadow. Acquisition of data: Nachman and Hodge. Analysis and interpretation of data: Nachman, Chernoff, Williams, and Gadow. Drafting of the manuscript: Nachman, Chernoff, Hodge, and Gadow. Critical revision of the manuscript for important intellectual content: Nachman, Chernoff, Williams, Heston, and Gadow. Statistical analysis: Nachman, Chernoff, and Williams. Obtained funding: Nachman, Williams, and Gadow. Administrative, technical, and material support: Nachman, Hodge, and Gadow. Study supervision: Nachman, Williams, and Gadow. Data management: Hodge.
Financial Disclosure: None reported.
Funding/Support: Overall support for IMPAACT was provided by grant U01 AI068632 from the National Institute of Allergy and Infectious Diseases (NIAID), the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), and grant AI068632 from the National Institute of Mental Health (NIMH). This work was supported by the Statistical and Data Analysis Center at Harvard School of Public Health under the National Institute of Allergy and Infectious Diseases cooperative agreements #5 U01 AI41110 with the Pediatric AIDS Clinical Trials Group (PACTG) and #1 U01 AI068616 with the IMPAACT Group. Support of the sites was provided by NIAID and the NICHD International and Domestic Pediatric and Maternal HIV Clinical Trials Network funded by NICHD (contract number N01-DK-9-001/HHSN267200800001C).
Disclaimer: The content of this article is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
Additional Information: The following institutions and individuals participated in IMPAACT P1055: 2901 (IMPAACT site code)—Division of Infectious Diseases, Harvard Medical School, Children's Hospital Boston, Boston, Massachusetts: Sandra Burchett; 3601—University of California, Los Angeles (UCLA)/Brazil AIDS Consortium Clinical Research Site (CRS): Karin Nielsen, Nicole Falgout, Joseph Geffen, and Jaime G. Deville; 3606—Miller Children's Hospital Long Beach, Long Beach Memorial Medical Center, Long Beach, California: Audra Deveikis; 3609—Division of Infectious Diseases, Department of Pediatrics, Harbor UCLA Medical Center: Margaret Keller; 3702—Division of Pediatrics, Immunology & Rheumatology, University of Maryland Medical Center, Baltimore: Vicki Tepper; 4001—Chicago Children's CRS, Chicago, Illinois: Ram Yogev; 4501—Pediatric AIDS CRS, University of California, San Francisco, San Francisco, California: Diane Wara; 4601—Maternal, Child, and Adolescent HIV CRS, University of California, San Diego: Stephen A. Spector, Lisa Stangl, Mary Caffery, and Rolando Viani; 4701—Pediatrics CRS, Duke University Medical Center, Durham, North Carolina: Kareema Whitfield, Sunita Patil, Joan Wilson, and Mary Jo Hassett; 5012—NICHD CRS, New York University, New York, New York: Sandra Deygoo, William Borkowsky, Sulachni Chandwani, and Mona Rigaud; 5013—NICHD CRS, Jacobi Medical Center, Bronx, New York: Andrew Wiznia; 5017—NICHD CRS, University of Washington, Seattle Children's Hospital, Seattle: Lisa Frenkel; 5018—NICHD CRS, University of South Florida, Tampa: Patricia Emmanuel, Jorge Lujan Zilberman, Carina Rodriguez, and Carolyn Graisbery; 5026—Mount Sinai School of Medicine, New York: Roberto Posada and Mary S. Dolan; 5031—NICHD CRS, San Juan City Hospital, San Juan, Puerto Rico: Midnela Acevedo-Flores, Lourdes Angeli, Milagros Gonzalez, and Dalila Guzman; 5038—Division of Infectious Diseases, Department of Pediatrics, Yale School of Medicine, New Haven, Connecticut: Warren A. Andiman, Leslie Hurst, and Anne Murphy; 5039—Department of Pediatrics, State University of New York (SUNY) Upstate Medical University, Syracuse: Leonard Weiner; 5040—NICHD CRS, SUNY Stony Brook, Stony Brook: Denise Ferraro, Michele Kelly, and Lorraine Rubino; 5044—NICHD CRS, Howard University, Washington, DC: Sohail Ranal; 5048—NICHD CRS, University of Southern California, Los Angeles: Suad Kapetanovic; 5051—NICHD CRS, University of Florida, Jacksonville: Mobeen H. Rathore, Ayesha Mirza, Kathleen Thoma, and Chas Griggs; 5052—NICHD CRS, University of Colorado, Denver: Robin McEvoy, Emily Barr, Suzanne Paul, and Patricia Michalek; 5055—NICHD CRS, South Florida CDC, Ft Lauderdale: Ana Puga; 6501—St Jude/University of Tennessee Health Science Center CRS: Patricia Garvie; 6701—IMPAACT CRS, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania: Richard Rutstein; 6704—Saint Christopher's Hospital for Children, Philadelphia: Roberta LaGuerre; 6901—IMPAACT CRS, Bronx-Lebanon Hospital Center, Bronx: Murli Purswani; 6905—Metropolitan Hospital Center, New York: Mahrukh Bamji; and 7301—Western New England Maternal Pediatric Adolescent AIDS CRS: Katherine Luzuriaga.
Additional Contributions: We acknowledge the helpful comments of anonymous reviewers. Kimberly Hudgens, MSHCA, MBA, provided operational support of this study.