Accepted for Publication: June 9, 2013.
Published Online: October 28, 2013. doi:10.1001/jamapediatrics.2013.3139.
Study concept and design: Luby, Botteron, Barch.
Acquisition of data: Luby, Botteron, Babb, Nishino, Barch.
Analysis and interpretation of data: Luby, Belden, Botteron, Marrus, Harms, Barch.
Drafting of the manuscript: Luby, Belden, Barch.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Belden, Harms, Barch.
Obtained funding: Luby, Botteron, Barch.
Administrative, technical, or material support: Luby, Botteron, Marrus, Harms, Babb, Nishino.
Study supervision: Luby, Botteron, Barch.
Conflict of Interest Disclosures: None reported.
Funding/Support: This study was supported by grants 2R01 MH064769-06A1 (Dr Luby) and PA-07-070 NIMH R01 (Drs Luby, Barch, and Botteron) from the National Institutes of Health. Dr Belden’s work on this manuscript was supported by grant 5K01MH090515-04 from the National Institutes of Health.
Role of the Sponsor: The funding source had no role in the design and conduct of the study; in the collection, analysis, and interpretation of the data; or in the preparation, review, or approval of the manuscript.
Additional Contributions: We wish to acknowledge our child participants and their parents whose participation and cooperation made this research possible. We thank Michael I. Miller, PhD, and Tilak Ratnanather, PhD, of the Center for Imaging Science, Johns Hopkins University, for their technical assistance and insights with the implementation of the large deformation diffeomorphic metric mapping to quantify the hippocampus and amygdala volumes.