This Viewpoint from the National Institutes of Health describes a new set of guidelines for the conduct and registration of clinical trials in the United States.
In this Viewpoint, John Ioannidis and colleagues review how rarely gene therapy and genomic medicine have led to breakthroughs for patients and call on the NIH to defund preclinical research that fails to deliver on its initial promise.
This study characterizes trends in the total number of clinical trials and in the proportion of trials funded by the National Institutes of Health and registered at ClinicalTrials.gov between 2006 and 2014.
This Viewpoint advocates initiating greater transparency in reporting results of clinical trials as a responsibility that will benefit the health of many.
This viewpoints reviews the health breakthroughs brought by the National Institutes of Health, considers new opportunities in research, and calls for adequate funding to ensure those promises are fulfilled.