This cohort study examines whether early-life antibiotic use in children is associated with the long-term effects of breastfeeding on weight development and lifetime antibiotic use.
This review examines the increasing incidence, evaluation, and management of pediatric nephrolithiasis.
This retrospective observational study reports that the risk for incident type 2 diabetes mellitus was increased among youths initiating second-generation antipsychotics and was highest in those concomitantly using antidepressants.
This cohort study tests the hypotheses that maternal folate concentrations can affect child metabolic health and that sufficient maternal folate concentrations can mitigate prepregnancy obesity-induced child metabolic risk.
This review article examines the current state of newborn screening for inborn errors of metabolism (IEMs), recent advances in therapy for IEMs, and opportunities for further exploration and discovery.
This cross-sectional study evaluates whether obese adolescents with metabolic syndrome have retinal vessel alterations and cerebral white matter microstructural damage.
Ho et al compare the effects of diet-only intervention with those of diet plus exercise or exercise only on weight loss and metabolic risk reduction in overweight children. In a related editorial, Crume and Harrod provide commentary.
This case-control study explores the potential association of congenital heart disease in offspring with maternal midpregnancy levels of glucose and insulin.
This review investigates current literature for treatment recommendations for cardiometabolic risk factors associated with polycystic ovary syndrome and finds potential for metformin and estrogen-progestin dual therapy, although longitudinal studies are warranted to determine its long-term effect on cardiovascular health.
This cross-sectional study describes risk factors associated with acute recurrent pancreatitis and chronic pancreatitis in children.
Shashaj et al assess whether insulin resistance and metabolic abnormalities are detectable at the onset of obesity and to unravel the interplay among adiposity, insulin resistance, and other such abnormalities. Patients with new-onset overweight or obesity underwent clinical laboratory testing and ultrasonographic investigations of fatty liver.
This cross-sectional study compares insulin sensitivity, measured with the hyperglycemic clamp technique, in adolescents with sleep deprivation vs those with adequate sleep.
This cohort study assesses the frequency with which parents experience patient safety incidents and the proportion of reported incidents that meet standard definitions of medical errors and preventable adverse events.