This randomized, open-label clinical trial shows that a combination of rifapentine and isoniazid was as effective as isoniazid alone in preventing tuberculosis in children aged 2 to 17 years, had a higher treatment completion rate, and was safe. See also the editorial by Marais.
Ferguson and colleagues’ nested case-control study aimed to assess the relationship between phthalate exposure during pregnancy and preterm birth. Shanna H. Swan, PhD, provided a related editorial.
Chemtob et al examine the association of maternal posttraumatic stress disorder (PTSD) and depression with child maltreatment and child exposure to traumatic events in the context of a pediatric primary care setting.
This birth cohort study provides evidence suggesting that prenatal but not postnatal exposure to bisphenol A is associated with diminished lung function and the development of persistent wheeze in children.
This review and meta-analysis determines the effectiveness of interventions delivered by health care professionals who provide routine child health care in reducing tobacco smoke exposure in children.
This population-based birth cohort study examines whether mild maternal hypothyroxinemia in early pregnancy is related to symptoms of attention-deficit/hyperactivity disorder in children at 8 years of age.
This prospective cohort study finds that few individual antiretrovirals and no drug classes were associated with an increased risk of congenital anomalies in HIV-exposed infants after adjustment for calendar year and maternal characteristics.
This ongoing cohort study reports that early probiotic supplementation may reduce the risk of islet autoimmunity in children at the highest genetic risk of type 1 diabetes mellitus.