This review investigates current literature for treatment recommendations for cardiometabolic risk factors associated with polycystic ovary syndrome and finds potential for metformin and estrogen-progestin dual therapy, although longitudinal studies are warranted to determine its long-term effect on cardiovascular health.
This study examines the biochemical link between the process of DNA methylation in gametes and autism.
Hobbs and coauthors report on the current state of the genetic epidemiology of birth defects and comment on future challenges and opportunities. They consider issues of study design and discuss common variant approaches, including candidate gene studies and genome-wide association studies. They also discuss the complexities embedded in exploring interactions between genes and the environment.