van der Pol and colleagues systematically review the literature to assess the efficacy and safety of histamine-2 receptor antagonists in pediatric gastroesophageal reflux disease.
Rosen and colleagues determine if acid suppression use results in gastric bacterial overgrowth, if there are changes in lung microflora associated with the use of gastric bacterial overgrowth, and if changes in lung microflora are related to full-column nonacid gastroesophageal reflux.
Indrio et al investigate whether oral supplementation with Lactobacillus reuteri DSM 17938 during the first 3 months of life can reduce the onset of colic, gastroesophageal reflux, and constipation in term newborns and thereby reduce the socioeconomic impact of these conditions.
In a literature review, Rosen discusses the latest controversies in the diagnosis and treatment of gastroesophageal reflux in infants.
Barnhart et al performed a retrospective, observational cohort study to compare the effect of fundoplication at the time of gastrostomy tube (GT) placement vs GT placement alone on subsequent reflux-related hospitalizations in 4163 infants with neurological impairment born between 2005 and 2010 at 42 US children’s hospitals.