This prospective cohort study reports that increasing body mass index and male sex increase relative risk of specific cardiovascular disease risk factors and suggests that even among severely obese adolescents, recognition and treatment of cardiovascular disease risk factors is important to help limit further progression of disease.
This study uses the cross-sectional National Health and Nutrition Examination Survey to examine the prevalence of and trends in dyslipidemia and adverse blood pressure among US children and adolescents.
Shashaj et al assess whether insulin resistance and metabolic abnormalities are detectable at the onset of obesity and to unravel the interplay among adiposity, insulin resistance, and other such abnormalities. Patients with new-onset overweight or obesity underwent clinical laboratory testing and ultrasonographic investigations of fatty liver.
Wong et al determine the safety and efficacy of dietary flaxseed supplementation in the management of hypercholesterolemia in children.
This Editorial discusses the US Preventive Services Task Force recommendation statement on screening for lipid disorders in children and adolescents.
This review investigates current literature for treatment recommendations for cardiometabolic risk factors associated with polycystic ovary syndrome and finds potential for metformin and estrogen-progestin dual therapy, although longitudinal studies are warranted to determine its long-term effect on cardiovascular health.
This longitudinal study evaluates the association of childhood psychosocial factors with adult coronary artery calcification among participants in the Cardiovascular Risk in Young Finns Study.
This cross-sectional study reports that application of pediatric guidelines for statin therapy in adolescents and young adults will increase the proportion of those eligible for treatment of elevated lipid levels.
This cross-sectional study evaluates whether obese adolescents with metabolic syndrome have retinal vessel alterations and cerebral white matter microstructural damage.