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  • Global Collaboration to Develop New and Existing Drugs for Neonates

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    JAMA Pediatr. 2015; 169(10):887-888. doi: 10.1001/jamapediatrics.2015.1640

    This Viewpoint discusses the specific areas that should be considered by global investigators when collaborating on the development of drugs for neonatal patients.

  • Unintended Consequences of Regulatory Initiatives in Childhood Cancer Drug Development

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    JAMA Pediatr. 2013; 167(10):886-887. doi: 10.1001/jamapediatrics.2013.2488
  • Adolescent Dosing and Labeling Since the Food and Drug Administration Amendments Act of 2007

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    JAMA Pediatr. 2013; 167(10):926-932. doi: 10.1001/jamapediatrics.2013.465

    Momper et al compared US Food and Drug Administration–approved adult and adolescent drug dosing and assessed the utility of allometric scaling for the prediction of drug clearance in the adolescent population.

  • Association of Antenatal Corticosteroids With Mortality, Morbidity, and Neurodevelopmental Outcomes in Extremely Preterm Multiple Gestation Infants

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    JAMA Pediatr. 2016; 170(6):593-601. doi: 10.1001/jamapediatrics.2016.0104

    This cohort study examines if use of antenatal corticosteroids is associated with improvement in major outcomes in extremely preterm multiples.

  • Surgery and Neurodevelopmental Outcome of Very Low-Birth-Weight Infants

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    JAMA Pediatr. 2014; 168(8):746-754. doi: 10.1001/jamapediatrics.2014.307

    Morriss et al assess the association between surgery during the initial hospitalization and death or neurodevelopmental impairment of very low-birth-weight infants. See the editorial by Williams et al.

  • Endocrine Effects of Inhaled Corticosteroids in Children

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    JAMA Pediatr. 2016; 170(2):163-170. doi: 10.1001/jamapediatrics.2015.3526

    This Review describes the endocrine effects of inhaled corticosteroids in children and the properties of the various formulations as they relate to these adverse outcomes.

  • Breastfeeding in Children of Women Taking Antiepileptic Drugs: Cognitive Outcomes at Age 6 Years

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    JAMA Pediatr. 2014; 168(8):729-736. doi: 10.1001/jamapediatrics.2014.118

    Meador et al examined the effects of antiepileptic drug exposure via breastfeeding on cognitive functions at age 6 years among 181 children for whom both breastfeeding and IQ data were available. All mothers in this analysis continued taking drug after delivery. Differential Ability Scales IQ was the primary outcome. See the editorial by Harden.

  • Influence of Surgeon Experience, Hospital Volume, and Specialty Designation on Outcomes in Pediatric Surgery: A Systematic Review

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    JAMA Pediatr. 2013; 167(5):468-475. doi: 10.1001/jamapediatrics.2013.25
    McAteer and colleagues reviewed the evidence regarding surgeon or hospital experience and their influence on outcomes in children’s surgery. See the commentary by Keren and Shah.
  • Fetal Surgery in the 1990s

    Abstract Full Text
    Am J Dis Child. 1989; 143(12):1431-1436. doi: 10.1001/archpedi.1989.02150240053016
  • Prospective Associations of Concerns About Physique and the Development of Obesity, Binge Drinking, and Drug Use Among Adolescent Boys and Young Adult Men

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    JAMA Pediatr. 2014; 168(1):34-39. doi: 10.1001/jamapediatrics.2013.2915

    Field et al investigate whether males with psychiatric symptoms related to eating and concern with physique are more likely to become obese, to start using drugs, to consume alcohol frequently, or to develop high levels of depressive symptoms.

  • Causes of Child and Youth Homelessness in Developed and Developing Countries: A Systematic Review and Meta-analysis

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    JAMA Pediatr. 2016; 170(5):435-444. doi: 10.1001/jamapediatrics.2016.0156

    This systematic review and meta-analysis reports on the self-reported reasons why children and youth around the world become street-involved.

  • Digital Support for Childbirth in Developing Countries: Seeds of Hope in an Evidential Desert

    Abstract Full Text
    JAMA Pediatr. 2016; 170(8):737-739. doi: 10.1001/jamapediatrics.2016.1010
  • Examining Infertility Treatment and Early Childhood Development in the Upstate KIDS Study

    Abstract Full Text
    JAMA Pediatr. 2016; 170(3):251-258. doi: 10.1001/jamapediatrics.2015.4164

    This cohort study assesses the use and type of infertility treatment in relation to children’s development through age 36 months.

  • Association Between Nonmedical Use of Prescription Drugs and Suicidal Behavior Among Adolescents

    Abstract Full Text
    JAMA Pediatr. 2016; 170(10):971-978. doi: 10.1001/jamapediatrics.2016.1802

    This cohort study investigates associations between nonmedical use of opioids, sedatives, or stimulants, and suicidal ideation and attempts among Chinese adolescents.

  • E-Cigarettes, Youth, and the US Food and Drug Administration’s “Deeming” Regulation

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    JAMA Pediatr. 2016; doi: 10.1001/jamapediatrics.2016.2255

    This Viewpoint discusses how the FDA can build upon the deeming rule to further protect youth by regulating e-cigarette advertising and flavors.

  • Lessons From Drugs to Devices: A Pediatric Perspective

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    JAMA Pediatr. 2015; 169(11):989-990. doi: 10.1001/jamapediatrics.2015.1932

    This Viewpoint discusses the need for development of pediatric medical devices.

  • Independent Evaluation of Middle School–Based Drug Prevention Curricula: A Systematic Review

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    JAMA Pediatr. 2015; 169(11):1046-1052. doi: 10.1001/jamapediatrics.2015.1736

    This systematic review discusses the outcomes of drug prevention programs used in middle schools as shown by independent evaluations.

  • Drug Dosing and Pharmacokinetics in Children With Obesity: A Systematic Review

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    JAMA Pediatr. 2015; 169(7):678-685. doi: 10.1001/jamapediatrics.2015.132

    This systematic review of the effects of obesity on drug disposition in children shows that clinically significant pharmacokinetic alternations are common in obese children. See also the Editorial by Gillman and Block.

  • Twelve-Dose Drug Regimen Now Also an Option for Preventing Tuberculosis in Children and Adolescents

    Abstract Full Text
    JAMA Pediatr. 2015; 169(3):208-210. doi: 10.1001/jamapediatrics.2014.3157
  • Drug Labeling and Exposure in Neonates

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    JAMA Pediatr. 2014; 168(2):130-136. doi: 10.1001/jamapediatrics.2013.4208

    Laughon et al quantify progress made in neonatal studies and neonatal information in product labeling as a result of recent legislation. See related editorial by Stiers and Ward.