This survey study demonstrated a placebo effect in a comparison of agave nectar, placebo, and no treatment for acute cough in infants and toddlers, with no additional benefit offered by agave nectar. See the Editorial by Taylor and Opel.
Rosen and colleagues determine if acid suppression use results in gastric bacterial overgrowth, if there are changes in lung microflora associated with the use of gastric bacterial overgrowth, and if changes in lung microflora are related to full-column nonacid gastroesophageal reflux.
This Review describes the endocrine effects of inhaled corticosteroids in children and the properties of the various formulations as they relate to these adverse outcomes.
This cohort study investigates associations between nonmedical use of opioids, sedatives, or stimulants, and suicidal ideation and attempts among Chinese adolescents.
This cohort study examines whether there is a difference in the proportion of unscheduled medical visits following emergency department discharge in infants who have bronchiolitis with vs without oxygen desaturations.
Wu et al compare the effect of nebulized 3% hypertonic saline vs 0.9% normal saline on admission rate and length of stay in infants with bronchiolitis. See also the editorial by Grewal and Klassen.
Williams et al validate administrative billing data for hospitalizations owing to childhood community-acquired pneumonia.
This review article summarizes the role of innate immunity in influenza A virus infection in the young child and highlights possible differences between children and adults that may make children more susceptible to severe influenza A infection.
Florin et al evaluate the effect of nebulized 3% hypertonic saline compared with normal saline on respiratory distress in infants with bronchiolitis not responding to standard treatments in the emergency department. See also the editorial by Grewal and Klassen.
Tapiainen and colleagues aimed to determine whether the antimicrobial treatment of acute otitis media (AOM) reduces the duration of middle ear effusion.