This study measures and compares the quality of resuscitative care delivered to simulated pediatric patients across a spectrum of pediatric emergency departments and general emergency departments in the United States.
This randomized clinical trial evaluates the effects of in-person resource navigation services vs written community resource information on social needs and child health.
This cohort study uses children with asthma in hospitals of varying sizes to design a template to match hospitals and patients for measurement of resource utilization.
This randomized clinical noninferiority trial compares heated, humidified high-flow nasal cannula (HHHFNC) vs standard nasal continuous positive airway pressure (CPAP) or bilevel nasal CPAP in treating respiratory distress syndrome of prematurity.
This study evaluates the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine’s effect over time among adolescents 11 to 18 years old and accounts for the transition from whole-cell to acellular pertussis vaccines for the childhood primary series.
This Viewpoint proposes that disclosures in comparative effectiveness randomized clinical trials should provide patients with appropriate information, including about risks, that are necessary to decide whether to join the trial, request a study treatment outside the trial, or select another available treatment.
This cluster-randomized clinical trial finds improved body mass index in groups of children whose physicians receive computerized clinical decision support and whose families receive coaching for behavior change.
This randomized pragmatic trial reports improved rates of up-to-date immunizations when primary care practices instituted a collaborative centralized reminder/recall. See also the Editorial comment by Fiks.
This retrospective cohort study suggests that clinicians reconsider the practice of treating otherwise healthy children with acute osteomyelitis with prolonged intravenous antibiotics when an equally effective oral alternative exists.
This Viewpoint addresses questions raised in the debate over whether the current US regulatory framework for governing protection of human research participants is an impediment to comparative effectiveness research.
This observational cohort study compares rates of neonatal morbidities and 18- to 22-month neurodevelopmental outcomes of extremely premature infants exposed to partial or complete courses of antenatal steroids vs those exposed to no antenatal steroids.
This study assesses the prevalence of type 2 diabetes and prediabetes in children with nonalcoholic fatty liver disease and assesses type 2 diabetes and prediabetes as risk factors for nonalcoholic steatohepatitis.
This cohort study examines if use of antenatal corticosteroids is associated with improvement in major outcomes in extremely preterm multiples.
This prospective, randomized, 2 × 2 factorial-design trial finds that the quality of CPR provided by health care professionals is poor. See the Editorial by Cook and Beckman.