This Medical Letter review summarizes appropriate alternative antibiotic treatment of sinusitis, bronchitis, and uncomplicated urinary tract infections in the wake of US Food and Drug Administration labeling changes warning of the risks of fluoroquinolones.
In this Special Communication, Anthony Fauci and colleagues review ecological factors contributing to, mechanisms of, and novel strategies to manage antimicrobial resistance.
This Viewpoint proposes that reminders about professional standards might prevent counterproductive responses of physicians to report card comparisons intended to improve health care quality and reduce waste.
This study describes the development and diagnostic accuracy of a host-response RNA signature for distinguishing bacterial from viral infection in febrile children younger than 5 years.
This Medical News article discusses the recent emergence of an antibiotic resistant superbug in US patients.
This pharmacoepidemiology study estimates the rate of outpatient, oral antibiotic prescribing by age and diagnosis in the United States and the estimated portion of antibiotic use that may be inappropriate in adults and children.
This cohort study assesses whether antibiotic exposure in the first 6 months of life is associated with weight gain among children followed up to age 7 years.
This Viewpoint explains the importance of optimized antibiotic use in controlling the increasing rate of illness, mortality, and morbidity resulting from antibiotic-resistant infections.
This systematic review characterizes associations between 3 aspects of antibiotic therapy (optimal time to antibiotic initiation, initial antibiotic selection, and criteria for the transition from intravenous to oral therapy) and short-term mortality in adults hospitalized with community-acquired pneumonia.
This cluster randomized clinical trial compares the effects of behavioral interventions on rates of inappropriate (not guideline-concordant) antibiotic prescribing during ambulatory visits for acute respiratory tract infections.
This Clinical Evidence Synopsis discusses whether oral or parenteral corticosteroids are associated with improved clinical outcomes in patients with acute sinusitis compared to placebo or standard clinical care.
This systematic review summarizes the diagnostic approaches for Clostridium difficile infection and evaluates which therapeutic approaches should be used.