This review article examines the current state of newborn screening for inborn errors of metabolism (IEMs), recent advances in therapy for IEMs, and opportunities for further exploration and discovery.
This study measures and compares the quality of resuscitative care delivered to simulated pediatric patients across a spectrum of pediatric emergency departments and general emergency departments in the United States.
This literature review provides an update on the current knowledge about Kawasaki disease as well as recent advances in its diagnosis and treatment.
This randomized clinical trial aims to determine whether providing donor milk instead of formula as supplemental feeding whenever own mother’s milk is insufficiently available during the first 10 days of life reduces the incidence of serious infection, necrotizing enterocolitis, and mortality.
This longitudinal study evaluates the association of childhood psychosocial factors with adult coronary artery calcification among participants in the Cardiovascular Risk in Young Finns Study.
Schwartz et al further validate the Social-ecological Model of Adolescent and Young Adult Readiness to Transition (SMART) via feedback from stakeholders (patients, parents, and providers) from a medically diverse population in need of life-long follow-up care, survivors of childhood cancer.
Bonafide et al evaluate the impact of pediatric rapid response system implementation inclusive of a medical emergency team and an early warning score on critical deterioration, a proximate outcome defined as unplanned transfer to the intensive care unit with noninvasive or invasive mechanical ventilation or vasopressor infusion in the 12 hours after transfer. Alobaidi and Joffe provide commentary in a related editorial.
Hobbs and coauthors report on the current state of the genetic epidemiology of birth defects and comment on future challenges and opportunities. They consider issues of study design and discuss common variant approaches, including candidate gene studies and genome-wide association studies. They also discuss the complexities embedded in exploring interactions between genes and the environment.
This recommendation statement from an expert panel describes a set of best practices for the diagnosis and evaluation of infants with Robin sequence.
This cross-sectional, discrete-choice survey demonstrates patterns of how parents prioritize the attributes of being a good parent for their seriously ill child, suggesting future research to better understand the origins and development of good-parent beliefs among these individuals.