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Picture of the Month Quiz

A 7-week-old boy presented with recurrent blisters in a linear configuration on the left posterior leg that were first noted at 3 days of age. Bacitracin ointment had been previously applied with no improvement. During the preceding few weeks, newer, "warty" papules developed in the same distribution. The patient was born via normal spontaneous vaginal delivery at 38 weeks' gestation following a pregnancy complicated by polyhydramnios and an abnormal triple screen. A prenatal diagnosis of Klinefelter syndrome (47, XXY) had been made.

Cutaneous examination at the time of presentation was significant for grouped vesicles and verrucous papules in a linear configuration along the left posterior leg (Figure). The remainder of the cutaneous examination was remarkable only for mild scalp scaling consistent with infantile seborrheic dermatitis. A skin biopsy was performed to confirm the diagnosis.

Image of grouped vesicles and verrucous papules in a linear configuration

Figure.

What is your diagnosis?

For a complete discussion read the Picture of the Month—Quiz Case.